منابع مشابه
Appendicectomy Complicated by Addisons Disease
requiring admission to ICU. Case report: A 33 year old male presented with a fifteen-hour history of vomiting, diarrhoea, and lower abdominal pain one week after a holiday in Portugal. He had no significant past medical history. On examination he had a tanned appearance, and was tender with guarding and rebound in the right iliac fossa. Rovsing’s sign was positive. He proceeded to theatre where...
متن کاملDesoxycorticosterone Acetate
1. Desoxycorticosterone acetate (DCA) and NaCl, in the dosage employed in normal rats, caused renal and cardiac hypertrophy, characteristic changes in the renal tubular epithelium, atrophic changes in the subcapsular zone of the adrenal cortex, and serum electrolyte changes characterized by a rise in sodium and fall in potassium. 2. In rats rendered nephritic with a rabbit anti-rat-kidney serum...
متن کاملAdjustment to aldosterone or desoxycorticosterone acetate induced sodium retention in patients with Addison's disease.
Long term administration of aldosterone (1) or desoxycorticosterone acetate (DCA) (2) to normal subjects has been shown, in certain instances, to produce continued renal potassium loss but only transient sodium and chloride retention. This adjustment of the renal response to sodium-retaining adrenal steroids has been termed an "escape" (3) from the expected effects of these compounds, and is se...
متن کاملDesoxycorticosterone Acetate and Wound Healing
The effect of desoxycorticosterone acetate (DCA) on the granulation tissue of healing and healed linear laparotomy wounds was studied in young adult male guinea pigs maintained on a complete diet and on a known intake of ascorbic acid. DCA induces the production of an excessive amount of granulation tissue, as evidenced by a relatively great number of fibroblasts and by a larger amount of groun...
متن کاملHypertensive cardiovascular disease induced by desoxycorticosterone in hypophysectomized rats bearing pituitary autotransplants.
The responsiveness of hypophyseetomized female rats bearing pituitary autotransplants to chronic, low dosage treatment with desoxycorticosterone acetate was compared with that of intact females. Intact animals reacted rapidly, developed malignant hypertension, and died within 10 weeks. By contrast hypophysectomized autograft-bearing rats developed hypertension more slowly, and the majority of t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1943
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4296.557